The reporter learned from the University of Science and Technology of China that the research team of Professor Liu Bo of the school used a two-dimensional layered material to develop a chiral separation membrane that can "grasp" the left-handed chiral molecules and "leave" the right-handed chiral molecules to separate. The efficiency is as high as 89%, and is expected to be industrialized. The results were published in "Nature · Newsletter".

In Journey to the West, the six-eared macaque and Sun Wukong stood together, and it was difficult to distinguish between heaven and earth. In the end, only Rulai Buddha screened out the fake Wukong true six ears, ensuring the smooth progress of the westward journey. A similar situation exists in biomolecules, the so-called isomers of different chiralities (enantiomers). The chemical formulas of the two molecules are exactly the same, but there are differences in the spatial structure, one is left-handed in space and the other is right-handed. The relationship between the two looks like left and right hands, and they look the same, but they cannot overlap. The effectiveness of enantiomers varies greatly. For example, L-amlodipine can treat high blood pressure, but dextro-amlodipine has no effect. In biopharmaceutical processes, chiral isomers are often prepared, but all that is needed is one of the chiral molecules, and the other is required to be completely removed.

Chiral separation membranes are currently a solution that has high hopes. According to reports, this separation membrane shows very obvious selectivity for different chiral enantiomers. It can efficiently separate d-limonene and retain most of the l-limonene. If further pressure is applied to the entire system, the separation efficiency can also be greatly improved in terms of timeliness, which can be used to achieve the efficient separation of enantiomers, thereby giving the two-dimensional material separation membrane a broader application prospect. (Reporter Wu Changfeng)

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